SMG9 Antibody - middle region
Catalog Number:
ASB-ARP97063_P050
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| Article Name: | SMG9 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP97063_P050 |
| Supplier Catalog Number: | ARP97063_P050 |
| Alternative Catalog Number: | ASB-ARP97063_P050-25UL,ASB-ARP97063_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human SMG9 |
| Alternative Names: | HBMS, C19orf61, F17127_1 |
| This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. |
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