SQSTM1 Antibody - middle region
Catalog Number:
ASB-ARP97313_P050
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| Article Name: | SQSTM1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP97313_P050 |
| Supplier Catalog Number: | ARP97313_P050 |
| Alternative Catalog Number: | ASB-ARP97313_P050-25UL,ASB-ARP97313_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1 |
| Alternative Names: | p60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3 |
| This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. |
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