RIPK3 Antibody - middle region

Product Overview

• Article Name: RIPK3 Antibody - middle region
• Biozol Catalog Number: ASB-AVARP00031_P050
• Supplier Catalog Number: AVARP00031_P050
• Alternative Catalog Number: ASB-AVARP00031_P050-25UL,ASB-AVARP00031_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Canine, Equine, Human, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RIPK3
• Alternative Names: RIP3

Product Description

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 52 kDa
• NCBI: 11035
• UniProt: Q9Y572
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Spleen

WB Suggested Anti-RIPK3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: PANC1 cell lysate

Host: Rat
Target Name: RIPK3
Sample Tissue: Rat Brain
Antibody Dilution: 1ug/ml

25 ug of the indicated Mouse or Rat tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. Protein may be phosporylated, and the peptide has 92% identity for the rat Ripk3 sequence.

RIPK3 antibody - middle region (AVARP00031_P050) in Human PANC1 using Western Blot