CFLAR Antibody - C-terminal region

Catalog Number: ASB-AVARP02011_P050
Article Name: CFLAR Antibody - C-terminal region
Biozol Catalog Number: ASB-AVARP02011_P050
Supplier Catalog Number: AVARP02011_P050
Alternative Catalog Number: ASB-AVARP02011_P050-25UL,ASB-AVARP02011_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human CFLAR
Alternative Names: CASH, FLIP, MRIT, CLARP, FLAME, cFLIP, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1
CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 55kDa
NCBI: 8837
UniProt: O15519
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.