AIFM1 Antibody - middle region

Product Overview

• Article Name: AIFM1 Antibody - middle region
• Biozol Catalog Number: ASB-AVARP02013_P050
• Supplier Catalog Number: AVARP02013_P050
• Alternative Catalog Number: ASB-AVARP02013_P050-25UL,ASB-AVARP02013_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AIFM1
• Alternative Names: AIF, AUNX1, CMT2D, CMTX4, COWCK, DFNX5, NADMR, NAMSD, PDCD8, COXPD6, SEMDHL

Product Description

AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 67kDa
• NCBI: 9131
• UniProt: O95831
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

WB Suggested Anti-AIFM1 Antibody
Titration: 1 ug/ml
Positive Control: Rat tissue

WB Suggested Anti-AIFM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysateAIFM1 is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: AIFM1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: AIFM1
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

AIFM1 antibody - middle region (AVARP02013_P050) in rat aorta using Western Blot