BAX Antibody - N-terminal region

Product Overview

• Article Name: BAX Antibody - N-terminal region
• Biozol Catalog Number: ASB-AVARP02020_T100
• Supplier Catalog Number: AVARP02020_T100
• Alternative Catalog Number: ASB-AVARP02020_T100-25UL,ASB-AVARP02020_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Human, Porcine
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BAX
• Alternative Names: BCL2L4

Product Description

BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 21kDa
• NCBI: 581
• UniProt: Q07812
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Immunohistochemistry with NT2, mouse brain, rat brain. tissue

Human kidney

Rabbit Anti-BAX Antibody
Catalog Number: AVARP02020
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X

WB Suggested Anti-BAX Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate

Lanes:
1. Human NT-2 cells (60ug) lysate 2. Mouse WT brain extract (80ug)
Primary Antibody Dilution:
2ug/ml
Secondary Antibody:
IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution:
1: 20,000
Gene Name:
BAX
Submitted by:
Dr. Yuzhi Chen, University of Arkansas for Medical Science

BAX antibody - N-terminal region (AVARP02020_T100) in Human HepG2 using Western Blot