FOS Antibody - N-terminal region

Product Overview

• Article Name: FOS Antibody - N-terminal region
• Biozol Catalog Number: ASB-AVARP04011_P050
• Supplier Catalog Number: AVARP04011_P050
• Alternative Catalog Number: ASB-AVARP04011_P050-25UL,ASB-AVARP04011_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Human, Mouse, Porcine, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOS
• Alternative Names: p55, AP-1, C-FOS

Product Description

The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The family members are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 41kDa
• NCBI: 2353
• UniProt: P01100
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Rabbit Anti-FOS Antibody
Catalog Number: AVARP04011_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Nucleus in hepatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-FOS Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation and phosphorylation.

Host: Rabbit
Target Name: FOS
Sample Tissue: Human PANC1 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: FOS
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: FOS
Sample Tissue: Human THP-1 Whole Cell
Antibody Dilution: 1ug/ml

FOS antibody - N-terminal region (AVARP04011_P050) in Human Muscle using Western Blot