HTR3A Antibody - N-terminal region

Product Overview

• Article Name: HTR3A Antibody - N-terminal region
• Biozol Catalog Number: ASB-AVARP13046_P050
• Supplier Catalog Number: AVARP13046_P050
• Alternative Catalog Number: ASB-AVARP13046_P050-25UL,ASB-AVARP13046_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3A
• Alternative Names: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R

Product Description

HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 55 kDa
• NCBI: 3359
• UniProt: P46098
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

WB Suggested Anti-HTR3A Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 5 ug/mL of the antibody was used in this experiment.

Host: Rabbit
Target Name: 5HT3A
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 5ug/ml

Host: Rabbit
Target Name: 5HT3A
Sample Type: RPMI-8226 lysates
Antibody Dilution: 1.0ug/ml

HTR3A antibody - N-terminal region (AVARP13046_P050) in Human Jurkat using Western Blot