This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from human ILK.
Alternative Names:
P59, ILK-1, ILK-2, p59ILK, HEL-S-28
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.