CYP3A4 Antibody - middle region
Catalog Number:
ASB-OAAB04841
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| Article Name: | CYP3A4 Antibody - middle region |
| Biozol Catalog Number: | ASB-OAAB04841 |
| Supplier Catalog Number: | OAAB04841 |
| Alternative Catalog Number: | ASB-OAAB04841-200UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | FC, IHC-P, WB |
| Species Reactivity: | Human |
| Immunogen: | This CYP3A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the Central region of human CYP3A4. |
| Alternative Names: | HLP, CP33, CP34, CYP3A, NF-25, VDDR3, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1 |
| CYP3A4, is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. |
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