ZNF281 Antibody - middle region
Catalog Number:
ASB-OAAB19078
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| Article Name: | ZNF281 Antibody - middle region |
| Biozol Catalog Number: | ASB-OAAB19078 |
| Supplier Catalog Number: | OAAB19078 |
| Alternative Catalog Number: | ASB-OAAB19078-400UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | This ZNF281 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 416-450 amino acids from the Central region of human ZNF281. |
| Alternative Names: | GZP1, ZBP99, ZBP-99, ZNP-99 |
| Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes. |
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