Htr2a Antibody - N-terminal region
Catalog Number:
ASB-OAAB19255
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| Article Name: | Htr2a Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-OAAB19255 |
| Supplier Catalog Number: | OAAB19255 |
| Alternative Catalog Number: | ASB-OAAB19255-400UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC-P, WB |
| Species Reactivity: | Mouse |
| Immunogen: | This Htr2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human Htr2a. |
| Alternative Names: | Htr, Htr-, Htr2, Htr-2, 5-HT-2, 5-HT-2A, E030013E04 |
| G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction. |
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