MCM2 Antibody
Catalog Number:
ASB-OAAB19721
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| Article Name: | MCM2 Antibody |
| Biozol Catalog Number: | ASB-OAAB19721 |
| Supplier Catalog Number: | OAAB19721 |
| Alternative Catalog Number: | ASB-OAAB19721-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ICC, IHC-P, WB |
| Species Reactivity: | Human |
| Alternative Names: | BM28, CCNL1, CDCL1, cdc19, DFNA70, D3S3194, MITOTIN |
| Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. |
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