PRPF19 Antibody
Catalog Number:
ASB-OAAB19750
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| Article Name: | PRPF19 Antibody |
| Biozol Catalog Number: | ASB-OAAB19750 |
| Supplier Catalog Number: | OAAB19750 |
| Alternative Catalog Number: | ASB-OAAB19750-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC-P, IP, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | PSO4, SNEV, PRP19, UBOX4, hPSO4, NMP200 |
| Plays a role in DNA double-strand break (DSB) repair. Binds double-stranded DNA in a sequence-nonspecific manner. Acts as a structural component of the nuclear framework. May also serve as a support for spliceosome binding and activity. Essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. May have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. |
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