CD86 Antibody, IgG1, Clone: [1B3], Mouse, Monoclonal
Catalog Number:
ASB-OAAD00377
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| Article Name: | CD86 Antibody, IgG1, Clone: [1B3], Mouse, Monoclonal |
| Biozol Catalog Number: | ASB-OAAD00377 |
| Supplier Catalog Number: | OAAD00377 |
| Alternative Catalog Number: | ASB-OAAD00377-0.1ML |
| Manufacturer: | Aviva |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | Purified recombinant fragment of human CD86 expressed in E. Coli. |
| Alternative Names: | B70, B7-2, B7.2, LAB72, CD28LG2 |
| This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes. |
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