GLP Antibody, IgG1, Clone: [1B7B4], Mouse, Monoclonal

Catalog Number: ASB-OAAD00421
Article Name: GLP Antibody, IgG1, Clone: [1B7B4], Mouse, Monoclonal
Biozol Catalog Number: ASB-OAAD00421
Supplier Catalog Number: OAAD00421
Alternative Catalog Number: ASB-OAAD00421-0.1MG
Manufacturer: Aviva
Host: Mouse
Category: Antikörper
Application: WB
Species Reactivity: Human
Alternative Names: GLP, GLP1, KMT1D, KLEFS1, FP13812, EHMT1-IT1, EUHMTASE1, Eu-HMTase1
Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and gluca- gon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogen- esis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
Clonality: Monoclonal
Clone Designation: [1B7B4]
Isotype: IgG1
NCBI: 79813
UniProt: Q9H9B1