CBP Antibody (Acetyl-Lys1535)
Catalog Number:
ASB-OAAF08189
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| Article Name: | CBP Antibody (Acetyl-Lys1535) |
| Biozol Catalog Number: | ASB-OAAF08189 |
| Supplier Catalog Number: | OAAF08189 |
| Alternative Catalog Number: | ASB-OAAF08189-100UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IF, IHC, IHC-P, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CBP around the acetylated site of Lys1535. |
| Alternative Names: | CBP,CREB-binding protein,histone lysine acetyltransferase CREBBP,KAT3A,MKHK1,protein-lysine acetyltransferase CREBBP,RSTS,RSTS1. |
| Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). |
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