Anti-Ephrin-B3 Polyclonal Antibody, Rabbit
Catalog Number:
ASB-OAAI00043
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| Article Name: | Anti-Ephrin-B3 Polyclonal Antibody, Rabbit |
| Biozol Catalog Number: | ASB-OAAI00043 |
| Supplier Catalog Number: | OAAI00043 |
| Alternative Catalog Number: | ASB-OAAI00043-100UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, FC, IHC, IP, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant full length (1-340aa) human Ephrin-B34 protein expressed in E.coli. |
| Alternative Names: | EFL6,EPH-related receptor transmembrane ligand ELK-L3,eph-related receptor tyrosine kinase ligand 8,ephrin-B3,EPLG8,LERK8. |
| Ehrin-B3, also known as EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It is highly expressed in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. The ephrin ligands and receptors have been divided into two major subclasses: Ephrin-A and ephrin-B. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
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