Anti-CD8 Polyclonal Antibody, Rabbit
Catalog Number:
ASB-OAAI00153
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| Article Name: | Anti-CD8 Polyclonal Antibody, Rabbit |
| Biozol Catalog Number: | ASB-OAAI00153 |
| Supplier Catalog Number: | OAAI00153 |
| Alternative Catalog Number: | ASB-OAAI00153-100UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, FC, IHC, IP, WB |
| Species Reactivity: | Human |
| Immunogen: | A synthetic peptide corresponding to C-terminus of human CD8 protein. |
| Alternative Names: | CD8,CD8 antigen, alpha polypeptide (p32),Leu2,Leu2 T-lymphocyte antigen,OKT8 T-cell antigen,p32,T cell co-receptor,T8 T-cell antigen,T-cell antigen Leu2,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2. |
| The CD8 antigen, also known as T8 or Leu2 or Lyt2 or T cell coreceptor, is a cell surface glycoprotein as a dimer with a molecular mass of 32 KD. It is found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The T8 antigen is expressed by the suppressor/cytotoxic subset of T lymphocytes which comprise most of the cortical thymocytes and approximately 30% of peripheral blood T cells. Studies have demonstRated that increased levels of T8+ cells are associated with viral infections such as hepatitis B, Epstein-Barr, and cytomegalovirus. This Antibody may be used in the study of cell-mediated cytotoxicity and that of immunoregulation and T-lymphocyte-mediated suppression. This Antibody stains CD8 (T8) antigen suppressor/cytotoxic T lymphocytes and majority of thymocytes (approximately 80%) in frozen tissue sections. |
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