A synthesized peptide derived from human CD130/gp130, corresponding to a region within C-terminal amino acids.
Alternative Names:
CD130, GP130, HIES4, CDW130, IL-6RB, sGP130
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors.