LIMK1 Antibody, Rabbit, Polyclonal
Catalog Number:
ASB-OAAJ03112
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| Article Name: | LIMK1 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-OAAJ03112 |
| Supplier Catalog Number: | OAAJ03112 |
| Alternative Catalog Number: | ASB-OAAJ03112-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IHC, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthesized peptide derived from human LIMK1/2 |
| Alternative Names: | LIMK, LIMK-1 |
| There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified. |
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