TLR4 Antibody, Rabbit, Polyclonal
Catalog Number:
ASB-OAAJ03257
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| Article Name: | TLR4 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ASB-OAAJ03257 |
| Supplier Catalog Number: | OAAJ03257 |
| Alternative Catalog Number: | ASB-OAAJ03257-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IHC, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthesized peptide derived from human TLR4 |
| Alternative Names: | TOLL, CD284, TLR-4, ARMD10 |
| Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria. |
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