The KLH conjugated peptide ISTLSCENK derived from IL-18, an augmentor of natural killer cell activity in the spleen and stimulator of interferon gamma production in Th1 cells.
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthes
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