A530045L16Rik,B7 homolog 1,B7h1,PD-,PDCD1 ligand 1,Pdcd1l,Pdcd1l1,Pdcd1lg1,Pdl1,programmed cell death 1 ligand 1.
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11238124). The PDCD1-mediated inhibito
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