2010010D16Rik,Cyclophilin E,cyclophilin-33,Cyp33,peptidyl-prolyl cis-trans isomerase E,PPIase E,rotamase E.
Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity, this requires proline isomerase activity.
