CD11a Antibody - PE Conjugated, IgG1, Clone: [B-B15], Mouse, Monoclonal
Biozol Catalog Number:
ASB-OADB00033
Supplier Catalog Number:
OADB00033
Alternative Catalog Number:
ASB-OADB00033-1ML
Manufacturer:
Aviva
Host:
Mouse
Category:
Antikörper
Application:
FC
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
CD11A, LFA-1, LFA1A
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.