DnaJ (Hsp40) homolog, subfamily B, member 1,dnaJ homolog subfamily B member 1,dnaJ protein homolog 1,Hdj1,heat shock 40 kDa protein 1,Hsp40,HSPF1,human DnaJ protein 1,radial spoke 16 homolog B,RSPH16B,Sis1.
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).