28 kDa heat shock protein,CMT2F,epididymis secretory protein Li 102,estrogen-regulated 24 kDa protein,heat shock 27 kDa protein,heat shock 27kD protein 1,heat shock 27kDa protein 1,heat shock protein beta-1,HEL-S-102,HMN2B,HS.76067,Hsp25,HSP27,HSP28,putative heat shock protein family B member 1 isoform,SRP27,stress-responsive protein 27.
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).