GZMB Antibody, IgG1, Clone: [CLB-GB11], Mouse, Monoclonal

Product Overview

• Article Name: GZMB Antibody, IgG1, Clone: [CLB-GB11], Mouse, Monoclonal
• Biozol Catalog Number: ASB-OAEE00403
• Supplier Catalog Number: OAEE00403
• Alternative Catalog Number: ASB-OAEE00403-0.1MG(C100)
• Manufacturer: Aviva
• Host: Mouse
• Category: Antikörper
• Application: FC
• Species Reactivity: Human, Primate
• Immunogen: Human NK cell line YT-INDY-derived granzyme B
• Alternative Names: C11,cathepsin G-like 1,CCPI,CGL1,CGL-1,CSPB,CSP-B,CTLA1,CTLA-1,CTSGL1,cytotoxic serine protease B,cytotoxic T-lymphocyte proteinase 2,fragmentin 2,Fragmentin-2,granzyme B,granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1),Granzyme-2,HLP,human lymphocyte protein,SECT,T-cell serine protease 1-3E.

Product Description

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Product Properties

• Clonality: Monoclonal
• Concentration: 1 mg/ml
• Clone Designation: [CLB-GB11]
• Isotype: IgG1
• NCBI: 3002
• UniProt: P10144
• Buffer: Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
• Purity: > 95% (by SDS-PAGE)
• Form: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide