TNFRSF10A Antibody

Product Overview

• Article Name: TNFRSF10A Antibody
• Biozol Catalog Number: ASB-OAEE00756
• Supplier Catalog Number: OAEE00756
• Alternative Catalog Number: ASB-OAEE00756-0.1MG(C100)
• Manufacturer: Aviva
• Host: Mouse
• Category: Proteine/Peptide
• Application: FC
• Species Reactivity: Human
• Immunogen: Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
• Conjugation: FITC
• Alternative Names: APO2,CD261,cytotoxic TRAIL receptor,death receptor 4,DR4,TNF-related apoptosis-inducing ligand receptor 1,TRAIL receptor 1,TRAILR1,TRAILR-1,TRAIL-R1,tumor necrosis factor receptor superfamily member 10A,tumor necrosis factor receptor superfamily member 10a variant 2,tumor necrosis factor receptor superfamily, member 10a.

Product Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Product Properties

• Clonality: Monoclonal
• Concentration: 0.1 mg/ml
• Clone Designation: [DR-4-02]
• Isotype: IgG1
• NCBI: 8797
• Buffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
• Form: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide