antigen identified by monoclonal antibody 1D8,antigenic surface determinant protein OA3,CD47 antigen (Rh-related antigen, integrin-associated signal transducer),CD47 glycoprotein,IAP,integrin associated protein,Integrin-associated protein,integrin-associated signal transducer,leukocyte surface antigen CD47,MER6,OA3,Protein MER6,Rh-related antigen.
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
The reagent is provided in Tris buffered saline (TBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Form:
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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