Recombinant protein encompassing a sequence within the C-terminus region of human RASA3. The exact sequence is proprietary.
Alternative Names:
GAPIII, GAP1IP4BP
This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants.
