Recombinant protein encompassing a sequence within the center region of human PHD4. The exact sequence is proprietary.
Alternative Names:
PH4, PH-4, PHD4, EGLN4, HIDEA, HIFPH4, P4H-TM
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.
