Recombinant protein encompassing a sequence within the center region of human ZNF408. The exact sequence is proprietary.
Alternative Names:
EVR6, RP72
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
