Recombinant Dengue virus NS1, a mixture of serotypes 1-4.
The NS1 protein is a major non-structural protein expressed by the Dengue Virus. The NS1 monomer is a glycosylated protein of approximately 45kD, which associates with lipids and forms a homoriimer inside infected cells. It is necessary for viral replication, and is also secreted into the extracellular space as a hexameric lipoprotein particle, which is involved in immune evasion and pathogenesis by interacting with components from both the innate and adaptive immune systems, as well as other host factors. NS1 is one of the major antigenic markers for viral infection with Dengue.
Clonality:
Monoclonal
Concentration:
Batch dependent. 1.5mg/ml.
Clone Designation:
[JE1.C10.H2.A9]
Isotype:
IgG1
Purity:
>95%
Form:
Phosphate Buffered Saline pH 7.4
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