DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.
Conjugation:
Unconjugated
Alternative Names:
acid DNase,deoxyribonuclease II alpha,deoxyribonuclease II, lysosomal,deoxyribonuclease-2-alpha,DNase II alpha,DNase II, lysosomal,DNASE2A,DNL,DNL2,lysosomal DNase II,R31240_2.
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
