ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS. The immunogen is located within the first 50 amino acids of ARTS.
Conjugation:
Unconjugated
Alternative Names:
apoptosis-related protein in the TGF-beta signaling pathway,ARTS,BRADEION,bradeion beta,brain protein H5,C17orf47,CE5B3,CE5B3 beta,cell division control-related protein 2,cerebral protein 7,H5,hCDCREL-2,hucep-7,MART,peanut-like protein 2,PNUTL2,SEP4,SEPT4,septin-4,septin-M,uncharacterized protein C17orf47.
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
