TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5. The immunogen is located within the last 50 amino acids of TTC5.
Conjugation:
Unconjugated
Alternative Names:
NEDCAFD,Strap,stress-responsive activator of p300,tetratricopeptide repeat protein 5,TPR repeat protein 5.
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
