PHAP antibody was raised with a synthetic peptide corresponding to amino acids at carboxy terminus of human PHAP I. The immunogen is located within the last 50 amino acids of PHAP.
Conjugation:
Unconjugated
Alternative Names:
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A,acidic leucine-rich nuclear phosphoprotein 32 family member A,acidic nuclear phosphoprotein pp32,C15orf1,cerebellar leucine rich acidic nuclear protein,epididymis secretory sperm binding protein,hepatopoietin Cn,HPPCn,I1PP2A,inhibitor-1 of protein phosphatase-2A,LANP,leucine-rich acidic nuclear protein,MAPM,mapmodulin,PHAP1,PHAPI,potent heat-stable protein phosphatase 2A inhibitor I1PP2A,PP32,putative HLA-DR-associated protein I,putative human HLA class II associated protein I.
Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
