ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT.
Conjugation:
Unconjugated
Alternative Names:
ECSIT homolog,ECSIT signalling integrator,evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial,likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved,Protein SITPEC,SITPEC.
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).