Rheb antibody was raised against a 15 amino acid synthetic peptide from the middle region of human Rheb. The immunogen is located within amino acids 40 - 90 of Rheb.
Conjugation:
Unconjugated
Alternative Names:
GTP-binding protein Rheb,Ras homolog enriched in brain,Ras homolog enriched in brain 2,RHEB2.
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
