AES antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human AES. The immunogen is located within the last 50 amino acids of AES.
Conjugation:
Unconjugated
Alternative Names:
AES,AES-1,AES-2,amino-terminal enhancer of split,ESP1,gp130-associated protein GAM,GRG,Grg-5,GRG5,groucho-related protein 5,Protein ESP1,Protein GRG,TLE family member 5.
Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
