TLR5 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TLR5. The immunogen is located within amino acids 450 - 500 of TLR5.
Conjugation:
Unconjugated
Alternative Names:
MELIOS,SLE1,SLEB1,systemic lupus erythematosus susceptibility 1,TIL3,toll/interleukin-1 receptor-like protein 3,toll-like receptor 5.
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
