Human TLR2 Antibody : Biotin, IgG2a, Clone: [2B4A1], Mouse, Monoclonal
Biozol Catalog Number:
ASB-OASB01310
Supplier Catalog Number:
OASB01310
Alternative Catalog Number:
ASB-OASB01310-0.1MG
Manufacturer:
Aviva
Host:
Mouse
Category:
Antikörper
Application:
FC
Species Reactivity:
Human
Immunogen:
Recombinant TLR2
Conjugation:
Biotin
Alternative Names:
TIL4, CD282
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the hosts inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
