Synthesized peptide derived from the N-terminal region of human RhoBTB1/2. Location: 30-110aa.
Alternative Names:
p83, DBC2, DEE64, EIEE64
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
