Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of S2808. Location: 2750-2830aa.
Alternative Names:
RyR, ARVC2, ARVD2, RYR-2, VTSIP
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.
