VRK1 ELISA Kit (Human)
Catalog Number:
ASB-OKCD00339
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| Article Name: | VRK1 ELISA Kit (Human) |
| Biozol Catalog Number: | ASB-OKCD00339 |
| Supplier Catalog Number: | OKCD00339 |
| Alternative Catalog Number: | ASB-OKCD00339-96WELLS |
| Manufacturer: | Aviva |
| Category: | Kits/Assays |
| Application: | ELISA |
| Species Reactivity: | Human |
| Alternative Names: | PCH1,PCH1A,serine/threonine-protein kinase VRK1,vaccinia related kinase 1,vaccinia virus B1R-related kinase 1,Vaccinia-related kinase 1. |
| Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates Thr-18 of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity. |
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