XPC ELISA Kit (Human)
Catalog Number:
ASB-OKCD01514
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| Article Name: | XPC ELISA Kit (Human) |
| Biozol Catalog Number: | ASB-OKCD01514 |
| Supplier Catalog Number: | OKCD01514 |
| Alternative Catalog Number: | ASB-OKCD01514-96WELLS |
| Manufacturer: | Aviva |
| Category: | Kits/Assays |
| Application: | ELISA |
| Species Reactivity: | Human |
| Alternative Names: | DNA repair protein complementing XP-C cells,mutant xeroderma pigmentosum group C,p125,RAD4,Xeroderma pigmentosum group C-complementing protein,xeroderma pigmentosum, complementation group C,XP3,XPCC. |
| Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. |
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