Fga ELISA Kit (Mouse)
Catalog Number:
ASB-OKCD01569
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| Article Name: | Fga ELISA Kit (Mouse) |
| Biozol Catalog Number: | ASB-OKCD01569 |
| Supplier Catalog Number: | OKCD01569 |
| Alternative Catalog Number: | ASB-OKCD01569-96WELLS |
| Manufacturer: | Aviva |
| Category: | Kits/Assays |
| Application: | ELISA |
| Species Reactivity: | Mouse |
| Alternative Names: | Fi,Fib,fibrinogen alpha chain,fibrinogen, A alpha polypeptide. |
| Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots (PubMed:7649481). In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization (PubMed:11389004). Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood (PubMed:7649481). However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo (PubMed:10930441). Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway (PubMed:19332769). Maternal fibrinogen is essential for successful pregnancy (PubMed:7649481). Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage (PubMed:12629066). May also facilitate the immune response via both innate and T-cell mediated pathways (PubMed:23487423). |
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