PTPRJ ELISA Kit (Human)
Catalog Number:
ASB-OKCD01590
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| Article Name: | PTPRJ ELISA Kit (Human) |
| Biozol Catalog Number: | ASB-OKCD01590 |
| Supplier Catalog Number: | OKCD01590 |
| Alternative Catalog Number: | ASB-OKCD01590-96WELLS |
| Manufacturer: | Aviva |
| Category: | Kits/Assays |
| Application: | ELISA |
| Species Reactivity: | Human |
| Alternative Names: | CD148,CD148 antigen,density-enhanced phosphatase 1,DEP1,DEP-1,HPTP eta,HPTPeta,human density enhanced phosphatase-1,protein tyrosine phosphatase, receptor type, J polypeptide,protein-tyrosine phosphatase eta,Protein-tyrosine phosphatase receptor type J,receptor-type tyrosine-protein phosphatase eta,R-PTP-ETA,R-PTP-J,SCC1,susceptibility to colon cancer 1, mouse, homolog of. |
| Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration, through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation, through KDR dephosphorylation. Negative regulator of EGFR signaling pathway, through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling. |
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